Extraction mechanism of ultrasound assisted extraction and its effect on higher yielding and purity of artemisinin crystals from Artemisia annua L. leaves

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Examining The Extraction Of Artemisinin From Artemisia Annua Using Ultrasound

Artemisinin suppresses the life-cycle of the plasmodium parasite which causes malaria. It is found naturally occurring within the trichome glands of the Artemisia annua plant. Traditional methods for extracting artemisinin are time-consuming and have high environmental impact due to the temperatures and organic solvents which must be employed. Ultrasound decreases these through acoustic streami...

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آنزیم تریپسین در شرایط قلیایی ناپایدار می باشد .و فعالیت پروتئولیتیکی تریپسین منجربه خود هضمی آن در جایگاههای خاصی می گردد. بنابر این آنزیمی با ناپایداری بالا محسوب میگردد. در سالهای اخیر موفق شدند که با ایجاد تغیرات شیمیایی با اضافه کردن فلزات خاص ، کلسیم و یا عمل استیلاسیون منجر به افزایش پایداری آنزیم تریپسین گردند. مطالعات در حال حاضر نشان می دهد که تریپسین استیله شده فعالیت آنزیمی خود را ...

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Extraction of the Antimalarial Artemisinin from Artemisia Annua L. Leaves with Supercritical Co2

The antimalarial artemisinin, the active principle of the plant Artemisia annua L., was extracted by Supercritical Fluid Extraction (SFE). Soxhlet extraction was studied as comparison processes. The extracts were analyzed by the indirect method GC-FID. The maximal extraction yield (1.82%DW) was obtained by SFE at T=40°C, P=200bar, CO2flow=4.5g/min, and 20% ethanol as modifier. The artemisinin e...

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A comparative study of ultrasound-assisted extraction (UAE) and hydro-distillation was performed for fast extraction of estragole from tarragon (Artemisia dracunculus L.) dried leaves. Several influential parameters of the UAE procedure in the extraction of estragole (type of solvent, extraction cycles, solvent to material ratio, irradiation time and particle size) were investigated an...

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ژورنال

عنوان ژورنال: Ultrasonics Sonochemistry

سال: 2017

ISSN: 1350-4177

DOI: 10.1016/j.ultsonch.2016.05.046